Refractive outcomes and complications after combined copolymer phakic intraocular lens explantation and phacoemulsification with intraocular lens implantation.
To report the use of intrastromal voriconazole injections combined with corneal debridement to treat deep recalcitrant fungal keratitis.
HISTORY AND SIGNS:
Three patients (2 female and 1 male) with culture proven fungal keratitis (1 Fusarium, 1 Candida, 1 Pseudallescheria boydii) were included in this study. The patients were treated with repeated intrastromal voriconazole (100 mg/1 ml) in combination with corneal debridement.
THERAPY AND OUTCOME:
The mean age of the patients was 65 years. The mean number of injections was 5. The patients were injected every 2-3 days. This technique required repeated corneal debridement to achieve complete resolution in these three cases.
Repeated intrastromal injection of voriconazole in combination with corneal debridement appears to be an effective and safe way to treat recalcitrant fungal keratitis, even in Fusarium keratitis.
Georg Thieme Verlag KG Stuttgart · New York.
+ Authors’ Information
Department of Ophthalmology, University of Lausanne, Fondation Asile des aveugles, Jules-Gonin Eye Hospital, Lausanne, Switzerland (Chair: Prof. Francine Behar-Cohen).
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